TOVINONTRINE ( IMR-687 )
Catalog No: 218701
CAS Number: 2062661-53-2
Purity: ≧98.0%
TOVINONTRINE ( IMR-687 ) is a highly selective and potent small molecule inhibitor of phosphodiesterase-9 (PDE9). Tovinontrine has a multimodal mechanism of action that acts primarily on red blood cells, or RBCs, and has the potential to act on white blood cells, or WBCs, adhesion mediators and other cell types.
For research use only. We do not sell to patients.
Chemical Information
| Name | TOVINONTRINE ( IMR-687 ) |
|---|---|
| Iupac Chemical Name | 6-{(3S,4S)-4-methyl-1-[(pyrimidin-2-yl)methyl]pyrrolidin-3-yl}-3-(oxan-4-yl)imidazo[1,5-a]pyrazin-8(7H)-one |
| Synonyms | IMR-687 ; TOVINONTRINE ; IMR687 ; IMR 687 |
| Molecular Formula | C21H26N6O2 |
| Molecular Weight | 394.479 |
| Smile | O=C1C2=CN=C(C3CCOCC3)N2C=C([C@@H]4CN(CC5=NC=CC=N5)C[C@H]4C)N1 |
| InChiKey | GWGNPYYVGANHRJ-GDBMZVCRSA-N |
| InChi | InChI=1S/C21H26N6O2/c1-14-10-26(13-19-22-5-2-6-23-19)11-16(14)17-12-27-18(21(28)25-17)9-24-20(27)15-3-7-29-8-4-15/h2,5-6,9,12,14-16H,3-4,7-8,10-11,13H2,1H3,(H,25,28)/t14-,16-/m1/s1 |
| CAS Number | 2062661-53-2 |
| Related CAS | 2062661-53-2 |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Off-white solid |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Handling | Avoid inhalation, contact with eyes and skin. Avoid dust and aerosol formation. Use only in areas with appropriate exhaust ventilation. |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code | 2934200090 |
Coming soon.
| Targets | Tovinontrine is a phosphodiesterase 9 (PDE9) inhibitor. |
|---|---|
| Mechanism | |
| Cell study | Sickle cell |
| Animal study | |
| Clinical study | Phase 2b |
Not available
Chemical Structure
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