VR23 is a small molecule that potently inhibited the activities of trypsin-like proteasomes (IC50 = 1 nM), chymotrypsin-like proteasomes (IC50 = 50-100 nM) and caspase-like proteasomes (IC50 = 3 M).
For research use only. We do not sell to patients.
Chemical Information
Name VR23
Iupac Chemical Name 7-chloro-4-(4-((2,4-dinitrophenyl)sulfonyl)piperazin-1-yl)quinoline
Synonyms VR-23; VR 23
Molecular Formula C19H16ClN5O6S
Molecular Weight 477.876
Smile O=S(N1CCN(C2=CC=NC3=CC(Cl)=CC=C32)CC1)(C4=C(C=C(C=C4)[N+]([O-])=O)[N+]([O-])=O)=O
InChiKey PDQVZPPIHADUOO-UHFFFAOYSA-N
InChi InChI=1S/C19H16ClN5O6S/c20-13-1-3-15-16(11-13)21-6-5-17(15)22-7-9-23(10-8-22)32(30,31)19-4-2-14(24(26)27)12-18(19)25(28)29/h1-6,11-12H,7-10H2
CAS Number 1624602-30-7
Related CAS
Ordering Information
Packaging Price Availability Purity Shipping Time
Bulk Enquiry Enquiry Enquiry
Formulation Solid powder
Purity 98%
Storage -20 ºC for 3 years
Solubility Soluble in DMSO
Handling
Shipping Condition Shipped under ambient temperature
HS Code
Targets
Mechanism
Cell study
Animal study
Clinical study