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VX-984 (M9831)

Catalog No: 2017879
CAS Number: 1562396-65-9
Purity: 98.0% 

VX-984, also known as M9831, is an ATP-competitive inhibitor of the catalytic subunit of DNA-dependent protein kinase (DNA-PK), with potential sensitizing and enhancing activities for both chemo- and radiotherapies. 

For research use only. We do not sell to patients.

Chemical Information

NameVX-984 (M9831)
Iupac Chemical Name8-[(1S)-2-[[6-(4,6-dideuterio-2-methylpyrimidin-5-yl)pyrimidin-4-yl]amino]-1-methylethyl]quinoline-4-carboxamide 
SynonymsVX-984;VX 984;VX984;M9831;M-9831;M 9831 
Molecular FormulaC22H19D2N7O 
Molecular Weight401.4702 
Smile[2H]C1=NC(=NC(=C1C1=CC(=NC=N1)NC[C@@H](C)C=1C=CC=C2C(=CC=NC12)C(=O)N)[2H])C
InChiKeyVVBJVVDVLYCIOI-PWIXWOBGSA-N
InChiInChI=1S/C22H21N7O/c1-13(16-4-3-5-17-18(22(23)30)6-7-24-21(16)17)9-27-20-8-19(28-12-29-20)15-10-25-14(2)26-11-15/h3-8,10-13H,9H2,1-2H3,(H2,23,30)(H,27,28,29)/t13-/m1/s1/i10D,11D
CAS Number1562396-65-9
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Ordering Information

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Formulationoff-white solid 
Purity98.0% 
Storage-20 ºC for 3 years 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

2017879 - VX-984 (M9831) | CAS 1562396-65-9

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