Vatalanib free base is an inhibitor of VEGFR2/KDR with IC50 of 37 nM, less potent against VEGFR1/Flt-1, 18-fold against VEGFR3/Flt-4.
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Chemical Information
Name | Vatalanib |
Iupac Chemical Name | N-(4-chlorophenyl)-4-(pyridin-4-ylmethyl)phthalazin-1-amine |
Synonyms | PTK787; PTK/ZK; CGP-79787; ZK-222584 |
Molecular Formula | C20H15ClN4 |
Molecular Weight | 346.813 |
Smile | C1=CC=C2C(=C1)C(=NN=C2NC3=CC=C(C=C3)Cl)CC4=CC=NC=C4 |
InChiKey | YCOYDOIWSSHVCK-UHFFFAOYSA-N |
InChi | InChI=1S/C20H15ClN4/c21-15-5-7-16(8-6-15)23-20-18-4-2-1-3-17(18)19(24-25-20)13-14-9-11-22-12-10-14/h1-12H,13H2,(H,23,25) |
CAS Number | 212141-54-3 |
Related CAS | |
Ordering Information
Packaging | Price | Availability | Purity | Shipping Time |
Bulk | | Enquiry | Enquiry | Enquiry |
Formulation | Solid powder |
Purity | 98% |
Storage | -20 ºC for 3 years |
Solubility | Soluble in DMSO |
Handling | |
Shipping Condition | Shipped under ambient temperature |
HS Code | |
Targets | |
Mechanism | |
Cell study | |
Animal study | |
Clinical study | |