WIKI4 is a novel Tankyrase inhibitor with IC50 of 15 nM for TNKS2, and leads to inhibition of Wnt/beta-catenin signaling.
For research use only. We do not sell to patients.
Chemical Information
Name | WIKI4 |
Iupac Chemical Name | 2-[3-[[4-(4-Methoxyphenyl)-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]thio]propyl]-1H-benz[de]isoquinoline-1,3(2H)-dione |
Synonyms | WIKI-4 |
Molecular Formula | C29H23N5O3S |
Molecular Weight | 521.59 |
Smile | COC1=CC=C(C=C1)N1C(=NN=C1C1=CC=NC=C1)SCCCN1C(C2=CC=CC=3C2=C(C1=O)C=CC3)=O |
InChiKey | RNUXIZKXJOGYQP-UHFFFAOYSA-N |
InChi | InChI=1S/C29H23N5O3S/c1-37-22-11-9-21(10-12-22)34-26(20-13-15-30-16-14-20)31-32-29(34)38-18-4-17-33-27(35)23-7-2-5-19-6-3-8-24(25(19)23)28(33)36/h2-3,5-16H,4,17-18H2,1H3 |
CAS Number | 838818-26-1 |
Related CAS | |
Ordering Information
Packaging | Price | Availability | Purity | Shipping Time |
Bulk | | Enquiry | Enquiry | Enquiry |
Formulation | Off-white solid powder |
Purity | 97% |
Storage | -20 ºC for 3 years |
Solubility | Soluble in DMSO |
Handling | |
Shipping Condition | Shipped under ambient temperature |
HS Code | |
Targets | |
Mechanism | |
Cell study | |
Animal study | |
Clinical study | |