WM-1119 is a highly potent, selective inhibitor of lysine acetyltransferase KAT6A with Kd of 2 nM, WM-1119 is a reversible competitor of acetyl coenzyme A and inhibits MYST-catalysed histone acetylation.
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Chemical Information
Name WM-1119
Iupac Chemical Name Benzoic acid, 3-fluoro-5-(2-pyridinyl)-, 2-[(2-fluorophenyl)sulfonyl]hydrazide
Synonyms WM-1119; WM 1119; WM1119;
Molecular Formula C18H13F2N3O3S
Molecular Weight 389.3768
Smile O=C(NNS(=O)(C1=CC=CC=C1F)=O)C2=CC(C3=NC=CC=C3)=CC(F)=C2
InChiKey QLXULUNLCRKWRD-UHFFFAOYSA-N
InChi InChI=1S/C18H13F2N3O3S/c19-14-10-12(16-6-3-4-8-21-16)9-13(11-14)18(24)22-23-27(25,26)17-7-2-1-5-15(17)20/h1-11,23H,(H,22,24)
CAS Number 2055397-28-7
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Ordering Information
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Formulation Off-white solid to white solid
Purity >98%
Storage Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility Soluble in DMSO
Handling
Shipping Condition Shipped under ambient temperature
HS Code
Targets
Mechanism
Cell study
Animal study
Clinical study