WYE-354 is a potent cell-permeable inhibitor of mTOR (IC50 = 4.3 nM) which blocks signaling through both mTOR complex 1 (mTORC1) and mTORC2.
For research use only. We do not sell to patients.
Name | WYE-354 |
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Iupac Chemical Name | methyl 4-(6-(4-((methoxycarbonyl)amino)phenyl)-4-morpholino-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate |
Synonyms | WYE354; WYE-354; WYE 354 |
Molecular Formula | C24H29N7O5 |
Molecular Weight | 495.53 |
Smile | COC(=O)NC1=CC=C(C=C1)C1=NC(=C2C(=N1)N(N=C2)C2CCN(CC2)C(=O)OC)N2CCOCC2 |
InChiKey | IMXHGCRIEAKIBU-UHFFFAOYSA-N |
InChi | InChI=1S/C24H29N7O5/c1-34-23(32)26-17-5-3-16(4-6-17)20-27-21(29-11-13-36-14-12-29)19-15-25-31(22(19)28-20)18-7-9-30(10-8-18)24(33)35-2/h3-6,15,18H,7-14H2,1-2H3,(H,26,32) |
CAS Number | 1062169-56-5 |
Related CAS |
Packaging | Price | Availability | Purity | Shipping Time |
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Bulk | Enquiry | Enquiry | Enquiry |
Formulation | Solid powder |
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Purity | 98% by HPLC |
Storage | -20 ºC for 3 years |
Solubility | Soluble in DMSO |
Handling | |
Shipping Condition | Shipped under ambient temperature |
HS Code |
Targets | |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |