XL765 is a PI3K/mTOR dual kinase inhibitor with IC50 values of 157 nM, 39 nM, 113 nM, 9 nM and 43 nM for mTOR, p110, p110, p110 and p110, respectively.
For research use only. We do not sell to patients.
Chemical Information
Name XL765
Iupac Chemical Name N-[4-[[3-(3,5-dimethoxyanilino)quinoxalin-2-yl]sulfamoyl]phenyl]-3-methoxy-4-methylbenzamide
Synonyms cc-497
Molecular Formula C31H29N5O6S
Molecular Weight 599.657
Smile CC1=C(C=C(C=C1)C(=O)NC2=CC=C(C=C2)S(=O)(=O)NC3=NC4=CC=CC=C4N=C3NC5=CC(=CC(=C5)OC)OC)OC
InChiKey HJSSPYJVWLTYHG-UHFFFAOYSA-N
InChi InChI=1S/C31H29N5O6S/c1-19-9-10-20(15-28(19)42-4)31(37)33-21-11-13-25(14-12-21)43(38,39)36-30-29(34-26-7-5-6-8-27(26)35-30)32-22-16-23(40-2)18-24(17-22)41-3/h5-18H,1-4H3,(H,32,34)(H,33,37)(H,35,36)
CAS Number 1123889-87-1
Related CAS
Ordering Information
Packaging Price Availability Purity Shipping Time
Bulk Enquiry Enquiry Enquiry
Formulation Solid powder
Purity 98%
Storage -20 ºC for 3 years
Solubility Soluble in DMSO
Handling
Shipping Condition Shipped under ambient temperature
HS Code
Targets
Mechanism
Cell study
Animal study
Clinical study