XMD16-5 is a novel tyrosine kinase nonreceptor 2(TNK2) inhibitor with IC50s of 16 nmol/L and 77 nmol/L for the D163E and R806Q mutations.
XMD16-5 is found to be potent in the inhibition of TNK2 phosphorylation. XMD8-87 and XMD16-5 potently inhibit phosphorylation of TNK2 truncation mutations found in solid tumor types.
For research use only. We do not sell to patients.
Name | XMD16-5 |
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Iupac Chemical Name | XMD16-5 |
Synonyms | N/A |
Molecular Formula | C23H24N6O2 |
Molecular Weight | 416.48 |
InChiKey | |
InChi | |
CAS Number | 1345098-78-3 |
Related CAS |
Packaging | Price | Availability | Purity | Shipping Time |
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Bulk | Enquiry | Enquiry | Enquiry |
Formulation | crystalline solid |
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Purity | 98% |
Storage | 3 years -20ºCpowder |
Solubility | Soluble in DMSO |
Handling | |
Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |