XMD8-92
Catalog No: 17030608
CAS Number: 1234480-50-2
Purity: 98%
XMD8-92 is a BMK1 inhibitor and a highly selective inhibitor of ERK5 activity. XMD8-92 inhibits pancreatic tumor xenograft growth via a DCLK1-dependent mechanism. XMD8-92 blocks cellular BMK1 activation and significantly suppresses tumor growth in lung and cervical tumor models and is well tolerated in animals.
For research use only. We do not sell to patients.
Chemical Information
| Name | XMD8-92 |
|---|---|
| Iupac Chemical Name | 2-[[2-ethoxy-4-(4-hydroxy-1-piperidinyl)phenyl]amino]-5,11-dihydro-5,11-dimethyl-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one |
| Synonyms | XMD8-92; XMD-8-92; XMD 8-92; XMD892; XMD-892; XMD 892 |
| Molecular Formula | C26H30N6O3 |
| Molecular Weight | 474.565 |
| Smile | C(C)OC1=C(C=CC(=C1)N1CCC(CC1)O)NC=1N=CC2=C(N(C3=C(C(N2C)=O)C=CC=C3)C)N1 |
| InChiKey | QAPAJIZPZGWAND-UHFFFAOYSA-N |
| InChi | InChI=1S/C26H30N6O3/c1-4-35-23-15-17(32-13-11-18(33)12-14-32)9-10-20(23)28-26-27-16-22-24(29-26)30(2)21-8-6-5-7-19(21)25(34)31(22)3/h5-10,15-16,18,33H,4,11-14H2,1-3H3,(H,27,28,29) |
| CAS Number | 1234480-50-2 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | off-white solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20ºCpowder |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
