XY1 is a very close analogue of SGC707 (a potent, selective, and non-competitive inhibitor of PRMT3 with IC50 of 31 nM), but XY1 is completely inactive.
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Chemical Information
Name XY1
Iupac Chemical Name 1-naphthalen-2-yl-3-(2-oxo-2-pyrrolidin-1-ylethyl)urea
Synonyms ZINC97306095; AKOS017213782
Molecular Formula C17H19N3O2
Molecular Weight 297.35
Smile C1CCN(C1)C(=O)CNC(=O)NC2=CC3=CC=CC=C3C=C2
InChiKey GSQHGSRPQHBTTP-UHFFFAOYSA-N
InChi InChI=1S/C17H19N3O2/c21-16(20-9-3-4-10-20)12-18-17(22)19-15-8-7-13-5-1-2-6-14(13)11-15/h1-2,5-8,11H,3-4,9-10,12H2,(H2,18,19,22)
CAS Number 1624117-53-8
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Ordering Information
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Formulation Solid powder
Purity 98%
Storage -20 ºC for 3 years
Solubility Soluble in DMSO
Handling
Shipping Condition Shipped under ambient temperature
HS Code
Targets
Mechanism
Cell study
Animal study
Clinical study