Y-27632 2Hcl is a selective ROCK1 (p160ROCK) inhibitor with Ki of 140 nM, exhibits >200-fold selectivity over other kinases, including PKC, cAMP-dependent protein kinase, MLCK and PAK.
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Chemical Information
Name Y-27632 dihydrochloride
Iupac Chemical Name 4-[(1R)-1-aminoethyl]-N-pyridin-4-ylcyclohexane-1-carboxamide;dihydrochloride
Synonyms Y 27632 dihydrochloride; Y27632 dihydrochloride
Molecular Formula C14H23Cl2N3O
Molecular Weight 320.258
Smile C[C@H](C1CCC(CC1)C(=O)NC2=CC=NC=C2)N.Cl.Cl
InChiKey IDDDVXIUIXWAGJ-DDSAHXNVSA-N
InChi InChI=1S/C14H21N3O.2ClH/c1-10(15)11-2-4-12(5-3-11)14(18)17-13-6-8-16-9-7-13;;/h6-12H,2-5,15H2,1H3,(H,16,17,18);2*1H/t10-,11?,12?;;/m1../s1
CAS Number 129830-38-2
Related CAS
Ordering Information
Packaging Price Availability Purity Shipping Time
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Formulation Solid powder
Purity 97%
Storage -20 ºC for 3 years
Solubility Soluble in DMSO
Handling
Shipping Condition Shipped under ambient temperature
HS Code
Targets
Mechanism
Cell study
Animal study
Clinical study