YF-2 hydrochloride is a highly selective, blood-brain-barrier permeable histone acetyltransferase activitor, acetylates H3 in the hippocampus, with EC50s of 2.75 μM, 29.04 μM and 49.31 μM for CBP, PCAF, and GCN5, respectively, shows no effect on HDAC. Anti-cancer and anti-Alzheimer's disease.
For research use only. We do not sell to patients.
Name | YF-2 hydrochloride |
---|---|
Synonyms | YF-2 hydrochloride;YF-2 HCI. |
Molecular Formula | C20H23Cl2F3N2O3 |
Molecular Weight | 467.31 |
Smile | O=C(NC1=CC=C(Cl)C(C(F)(F)F)=C1)C2=C(OCC)C=CC=C2OCCN(C)C.Cl |
InChiKey | |
InChi | |
CAS Number | 1312005-62-1 |
Related CAS |
Packaging | Price | Availability | Purity | Shipping Time |
---|---|---|---|---|
Bulk | Enquiry | Enquiry | Enquiry |
Formulation | Off-white solid to white solid |
---|---|
Purity | >98% |
Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
Solubility | Soluble in DMSO |
Handling | |
Shipping Condition | Shipped under ambient temperature |
HS Code |
Targets | |
---|---|
Mechanism | |
Cell study | |
Animal study | |
Clinical study |