Zasocitinib is under development for the treatment of moderate to severe plaque psoriasis, psoriatic arthritis, inflammatory bowel disease (IBD) including crohn's disease (regional enteritis), ulcerative colitis and systemic lupus erythematosus. The drug candidate acts by targeting nonreceptor tyrosine protein kinase (TYK2).
For research use only. We do not sell to patients.
Name | Zasocitinib |
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Iupac Chemical Name | N-[(1R,2R)-2-Methoxycyclobutyl]-7-(methylamino)-5-[(2-oxo-2H-[1,2'-bipyridin]-3-yl)amino]pyrazolo[1,5-a]pyrimidine-3-carboxamide |
Synonyms | Zasocitinib ; NDI-034858; TAK-279 ; |
Molecular Formula | C23H24N8O3 |
Molecular Weight | 460.50 |
Smile | O=C(C1=C2N=C(NC3=CC=CN(C4=NC=CC=C4)C3=O)C=C(NC)N2N=C1)N[C@H]5[C@H](OC)CC5 |
InChiKey | BWINBHTTZLVXGT-NVXWUHKLSA-N |
InChi | InChI=1S/C23H24N8O3/c1-24-20-12-18(27-16-6-5-11-30(23(16)33)19-7-3-4-10-25-19)29-21-14(13-26-31(20)21)22(32)28-15-8-9-17(15)34-2/h3-7,10-13,15,17,24H,8-9H2,1-2H3,(H,27,29)(H,28,32)/t15-,17-/m1/s1 |
CAS Number | 2272904-53-5 |
Related CAS | 2272904-53-5 |
Packaging | Price | Availability | Purity | Shipping Time |
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Bulk | Enquiry | Enquiry | Enquiry |
Formulation | Solid powder |
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Purity | ≧98.0% |
Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
Solubility | Soluble in DMSO |
Handling | Refer to MSDS |
Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
HS Code | 2934200090 |
Targets | |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |