Zilurgisertib (earlier known as INCB 00928) is an activin receptor-like kinase-2 (ALK2, also known as ACVR1) inhibitor, being developed by Incyte Corporation.
For research use only. We do not sell to patients.
Name | Zilurgisertib |
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Iupac Chemical Name | 2-amino-N-(4-hydroxybicyclo[2.2.2]octan-1-yl)-5-(4-((1R,5S)-3-(tetrahydro-2H-pyran-4-yl)-3-azabicyclo[3.1.0]hexan-1-yl)phenyl)nicotinamide |
Synonyms | Zilurgisertib ; Zilurgisertibum ; INCB-000928 ; NBU-928 |
Molecular Formula | C30H38N4O3 |
Molecular Weight | 502.65 |
Smile | O=C(C1=CC(C2=CC=C([C@]34CN(C5CCOCC5)C[C@@]3([H])C4)C=C2)=CN=C1N)NC6(CC7)CCC7(O)CC6 |
InChiKey | KPRPFTOLWQQUAV-OCVAFRRMSA-N |
InChi | InChI=1S/C30H38N4O3/c31-26-25(27(35)33-28-7-10-29(36,11-8-28)12-9-28)15-21(17-32-26)20-1-3-22(4-2-20)30-16-23(30)18-34(19-30)24-5-13-37-14-6-24/h1-4,15,17,23-24,36H,5-14,16,18-19H2,(H2,31,32)(H,33,35)/t23-,28?,29?,30+/m1/s1 |
CAS Number | 2173389-57-4 |
Related CAS | Zilurgisertib |
Packaging | Price | Availability | Purity | Shipping Time |
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Bulk | Enquiry | Enquiry | Enquiry |
Formulation | Solid powder |
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Purity | ≧98.0% |
Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
Solubility | Soluble in DMSO |
Handling | Refer to MSDS |
Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
HS Code | 2934200090 |
Targets | |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |