Zongertinib [BI 1810631] is a human epidermal growth factor receptor 2 (HER2) inhibitor that covalently binds to the tyrosine kinase domain of both wild type and mutated HER2 receptors, including those with an exon 20 insertion.
For research use only. We do not sell to patients.
Name | Zongertinib |
---|---|
Iupac Chemical Name | N-[1-(8-[3-Methyl-4-[(1-methyl-1H-benzimidazol-5-yl)oxy]anilino]pyrimido[5,4-d]pyrimidin-2-yl)piperidin-4-yl]prop-2-enamide |
Synonyms | BI 1810631 ; BI1810631 ; BI-1810631 ; Zongertinib |
Molecular Formula | C29H29N9O2 |
Molecular Weight | 535.61 |
Smile | C=CC(NC1CCN(C2=NC=C(N=CN=C3NC4=CC=C(OC5=CC=C6C(N=CN6C)=C5)C(C)=C4)C3=N2)CC1)=O |
InChiKey | YSGNGFPNTLERCR-UHFFFAOYSA-N |
InChi | InChI=1S/C29H29N9O2/c1-4-26(39)34-19-9-11-38(12-10-19)29-30-15-23-27(36-29)28(32-16-31-23)35-20-5-8-25(18(2)13-20)40-21-6-7-24-22(14-21)33-17-37(24)3/h4-8,13-17,19H,1,9-12H2,2-3H3,(H,34,39)(H,31,32,35) |
CAS Number | 2728667-27-2 |
Related CAS | 2728667-27-2 |
Packaging | Price | Availability | Purity | Shipping Time |
---|---|---|---|---|
Bulk | Enquiry | Enquiry | Enquiry |
Formulation | Solid powder |
---|---|
Purity | ≧98.0% |
Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
Solubility | Soluble in DMSO |
Handling | Refer to MSDS |
Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
HS Code | 2934200090 |
Targets | |
---|---|
Mechanism | |
Cell study | |
Animal study | |
Clinical study |