Zunsemetinib is an investigational oral mitogen-activated protein kinase-activated protein kinase 2 (MK2) inhibitor.
For research use only. We do not sell to patients.
Name | Zunsemetinib |
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Iupac Chemical Name | (S)-3-chloro-4-((3,5-difluoropyridin-2-yl)methoxy)-2'-(2-(2-hydroxypropan-2-yl)pyrimidin-4-yl)-5',6-dimethyl-2H-[1,4'-bipyridin]-2-one |
Synonyms | Zunsemetinib ; ATI-450 ; CDD-450 |
Molecular Formula | C25H22ClF2N5O3 |
Molecular Weight | 513.93 |
Smile | CC(C1=NC=CC(C2=C[C@@]([N@@]3C(C)=CC(OCC4=NC=C(F)C=C4F)=C(Cl)C3=O)=C(C)C=N2)=N1)(O)C |
InChiKey | FQPQMJULRZINPV-UHFFFAOYSA-N |
InChi | InChI=1S/C25H22ClF2N5O3/c1-13-10-30-18(17-5-6-29-24(32-17)25(3,4)35)9-20(13)33-14(2)7-21(22(26)23(33)34)36-12-19-16(28)8-15(27)11-31-19/h5-11,35H,12H2,1-4H3 |
CAS Number | 1640282-42-3 |
Related CAS | 1640282-42-3 |
Packaging | Price | Availability | Purity | Shipping Time |
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Bulk | Enquiry | Enquiry | Enquiry |
Formulation | Solid powder |
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Purity | ≧98.0% |
Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
Solubility | Soluble in DMSO (DMSO : ≥ 100 mg/mL) |
Handling | Refer to MSDS |
Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
HS Code | 2934200090 |
Targets | |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |