kobe2602 is a novel and effective small-molecule compound inhibiting RasCRaf interaction by SBDD; exhibits potent activity to competitively inhibit the binding of H-RasGTP to c-Raf-1 RBD with a Ki value of 149 55 M.
For research use only. We do not sell to patients.
Name | kobe2602 |
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Iupac Chemical Name | 2-(2,6-dinitro-4-(trifluoromethyl)phenyl)-N-(4-fluorophenyl)hydrazinecarbothioamide |
Synonyms | N/A |
Molecular Formula | C14H9F4N5O4S |
Molecular Weight | 419.31 |
Smile | FC(C1=CC([N+]([O-])=O)=C(NNC(NC2=CC=C(F)C=C2)=S)C([N+]([O-])=O)=C1)(F)F |
InChiKey | NNPBSITXCGPXJC-UHFFFAOYSA-N |
InChi | InChI=1S/C14H9F4N5O4S/c15-8-1-3-9(4-2-8)19-13(28)21-20-12-10(22(24)25)5-7(14(16,17)18)6-11(12)23(26)27/h1-6,20H,(H2,19,21,28) |
CAS Number | 454453-49-7 |
Related CAS |
Packaging | Price | Availability | Purity | Shipping Time |
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Bulk | Enquiry | Enquiry | Enquiry |
Formulation | crystalline solid |
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Purity | 98% |
Storage | 3 years -20ºCpowder |
Solubility | Soluble in DMSO |
Handling | |
Shipping Condition | Shipped under ambient temperature |
HS Code |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |