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A-366

编号: 16122743
Cas号: 1527503-11-2
纯度: 98% 

A-366 is a potent and selective G9a/GLP histone lysine methyltransferase inhibitor with IC50 of 3.3nM, exhibiting >1000-fold selectivity for G9a/GLP over 21 other methyltransferases.A-366 has significantly less cytotoxic effects on the growth of tumor cell lines compared to other known G9a/GLP small molecule inhibitors despite equivalent cellular activity on methylation of H3K9me2. Treatment of various leukemia cell lines in vitro results in marked differentiation and morphological changes of these tumor cell lines 

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化学信息

名称A-366
Iupac 化学名称A-366 
同义词N/A 
英文同义词N/A 
分子式C19H27N3O2 
分子量329.44 
InChiKey
InChi
Cas号1527503-11-2
相关CAS号

订购信息

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外观性状crystalline solid 
纯度98% 
存储3 years -20ºCpowder 
可溶性Soluble in DMSO 
处理方式
运输条件Shipped under ambient temperature as non-hazardous chemical. 
海关编码
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

化学结构

16122743 - A-366 | CAS 1527503-11-2

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