AGN 196996 is a potent and selective RARα antagonist with Ki value of 2 nM; little binding affinity for RARβ(Ki=1087 nM) and RARγ(Ki=8523 nM).
仅供研究使用。 我们不向患者出售。
Name | AGN 196996 |
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Iupac Chemical Name | 4-(3-bromo-4-ethoxy-5-(4-methylbenzoyl)benzamido)benzoic acid |
Synonyms | AGN 196996 ; AGN-196996 ; AGN196996 ; |
英文同义词 | AGN 196996 ; AGN-196996 ; AGN196996 ; |
Molecular Formula | C24H20BrNO5 |
Molecular Weight | 482.33 |
Smile | O=C(O)C1=CC=C(NC(C2=CC(C(C3=CC=C(C)C=C3)=O)=C(OCC)C(Br)=C2)=O)C=C1 |
InChiKey | BUGXGZOGQGUTBC-UHFFFAOYSA-N |
InChi | InChI=1S/C24H20BrNO5/c1-3-31-22-19(21(27)15-6-4-14(2)5-7-15)12-17(13-20(22)25)23(28)26-18-10-8-16(9-11-18)24(29)30/h4-13H,3H2,1-2H3,(H,26,28)(H,29,30) |
CAS Number | 958295-17-5 |
相关CAS号 | 958295-17-5 |
包装 | Price | 库存 | Purity | 备货期 |
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大货 | Enquiry | Enquiry | Enquiry |
外观性状 | Off-white solid to white powder |
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Purity | ≧98.0% |
Storage | Dry, dark and at 0-4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Solubility | Soluble in CDCl3, MeOH etc. |
处理方式 | Refer to MSDS operation |
Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
海关编码 | 2934200090 |
Targets | RARα antagonist |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |