AM-9747
编号: 24018
Cas号: 2691869-82-4
纯度: ≧98.0%
AM-9747 is an MTA cooperative PRMT5 inhibitor. AM-9747 selectively inhibited the proliferation of HCT116 MTAP-deleted cells (IC50 = 0.027 μM).
仅供研究使用。 我们不向患者出售。
化学信息
| 名称 | AM-9747 |
|---|---|
| Iupac 化学名称 | 2-Amino-3-methyl-N-[(1R)-1-(pyrimidin-2-yl)ethyl]-N-[[5-(trifluoromethyl)pyridin-2-yl]methyl]quinoline-6-carboxamide |
| 同义词 | AM-9747 ; AM 9747 ; AM9747 |
| 英文同义词 | AM-9747 ; AM 9747 ; AM9747 |
| 分子式 | C24H21F3N6O |
| 分子量 | 466.47 |
| Smile | O=C(C1=CC=C2N=C(N)C(C)=CC2=C1)N([C@@H](C3=NC=CC=N3)C)CC4=NC=C(C(F)(F)F)C=C4 |
| InChiKey | QRZCNKOBDDQUAP-OAHLLOKOSA-N |
| InChi | InChI=1S/C24H21F3N6O/c1-14-10-17-11-16(4-7-20(17)32-21(14)28)23(34)33(15(2)22-29-8-3-9-30-22)13-19-6-5-18(12-31-19)24(25,26)27/h3-12,15H,13H2,1-2H3,(H2,28,32)/t15-/m1/s1 |
| Cas号 | 2691869-82-4 |
| 相关CAS号 | 2691869-82-4 |
订购信息
| 包装 | 价格 | 库存 | 纯度 | 备货期 |
|---|---|---|---|---|
| 大货 | 询价 | 询价 | 询价 |
| 外观性状 | Solid powder |
|---|---|
| 纯度 | ≧98.0% |
| 存储 | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| 可溶性 | Soluble in DMSO (DMSO : ≥ 100 mg/mL) |
| 处理方式 | Refer to MSDS |
| 运输条件 | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| 海关编码 | 2934200090 |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
