ARS-853 is a selective, covalent inhibitor of KRAS-G12C that inhibits mutant KRAS driven signaling by binding to the GDP bound oncoprotein and preventing activation.
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化学信息
名称 | ARS-853 |
同义词 | ARS853 |
英文同义词 | ARS853 |
分子式 | C22H29ClN4O3 |
分子量 | 432.94 |
InChiKey | |
InChi | |
Cas号 | 1629268-00-3 |
相关CAS号 | |
外观性状 | Solid powder |
纯度 | 98% by HPLC |
存储 | -20 ºC for 3 years |
可溶性 | Soluble in DMSO |
处理方式 | |
运输条件 | Shipped under ambient temperature |
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Cell study | |
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