AV-412 is an EGFR/HER2 inhibitor that binds to and inhibits the epidermal growth factor receptor (EGFR) and the human epidermal growth factor receptor 2 (HER2), which may result in the inhibition of tumor growth and angiogenesis.
AV-412(Free base) and AV-412 Tosylate, Bulk in stock, contact us by email for the bulk quotation.
仅供研究使用。 我们不向患者出售。
名称 | AV-412 |
---|---|
Iupac 化学名称 | N-(4-((3-chloro-4-fluorophenyl)amino)-7-(3-methyl-3-(4-methylpiperazin-1-yl)but-1-yn-1-yl)quinazolin-6-yl)acrylamide |
同义词 | AV412 ; AV 412; MP412; MP-412 |
英文同义词 | AV412 ; AV 412; MP412; MP-412 |
分子式 | C27H28ClFN6O |
分子量 | 507.00 |
Smile | C=CC(NC1=CC2=C(NC3=CC=C(F)C(Cl)=C3)N=CN=C2C=C1C#CC(N4CCN(C)CC4)(C)C)=O |
InChiKey | ZAJXXUDARPGGOC-UHFFFAOYSA-N |
InChi | InChI=1S/C27H28ClFN6O/c1-5-25(36)33-23-16-20-24(30-17-31-26(20)32-19-6-7-22(29)21(28)15-19)14-18(23)8-9-27(2,3)35-12-10-34(4)11-13-35/h5-7,14-17H,1,10-13H2,2-4H3,(H,33,36)(H,30,31,32) |
Cas号 | 451492-95-8 |
相关CAS号 | 451493-31-5 ( AV-412 Tosylate ) |
包装 | 价格 | 库存 | 纯度 | 备货期 |
---|---|---|---|---|
大货 | 询价 | 询价 | 询价 |