AVL-292 is a covalent, highly selective, orally active small molecule inhibitor of Btk with IC50 value of 0.5 nM; >1400-fold selectivity over the other kinases assayed.
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化学信息
名称 | AVL-292 |
分子式 | C22H22FN5O3 |
分子量 | 423.44 |
InChiKey | |
InChi | |
Cas号 | 1202757-89-8 |
相关CAS号 | |
纯度 | 98% |
可溶性 | DMSO 80 mg/ml; Water <1 mg/ml |
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