AVN944
编号: 022201
Cas号: 297730-17-7
纯度: 98%
AVN944 is an orally available, synthetic small molecule with potential antineoplastic activity, which inhibits inosine monosphosphate dehydrogenase (IMPDH), an enzyme involved in the de novo synthesis of guanosine triphosphate (GTP), a purine molecule required for DNA and RNA synthesis. Inhibition of IMPDH deprives cancer cells of GTP, resulting in disruption of DNA and RNA synthesis, inhibition of cell proliferation, and the induction of apoptosis.
仅供研究使用。 我们不向患者出售。
化学信息
| 名称 | AVN944 |
|---|---|
| Iupac 化学名称 | [(2R)-1-cyanobutan-2-yl] N-[(1S)-1-[3-[[3-methoxy-4-(1,3-oxazol-5-yl)phenyl]carbamoylamino]phenyl]ethyl]carbamate |
| 同义词 | AVN-944; AVN 944; VX944; VX 944; VX-944 |
| 英文同义词 | AVN-944; AVN 944; VX944; VX 944; VX-944 |
| 分子式 | C25H27N5O5 |
| 分子量 | 477.512 |
| Smile | O=C(O[C@H](CC)CC#N)N[C@H](C1=CC=CC(NC(NC2=CC=C(C3=CN=CO3)C(OC)=C2)=O)=C1)C |
| InChiKey | GYCPCOJTCINIFZ-OXJNMPFZSA-N |
| InChi | InChI=1S/C25H27N5O5/c1-4-20(10-11-26)35-25(32)28-16(2)17-6-5-7-18(12-17)29-24(31)30-19-8-9-21(22(13-19)33-3)23-14-27-15-34-23/h5-9,12-16,20H,4,10H2,1-3H3,(H,28,32)(H2,29,30,31)/t16-,20+/m0/s1 |
| Cas号 | 297730-17-7 |
| 相关CAS号 |
订购信息
| 包装 | 价格 | 库存 | 纯度 | 备货期 |
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| 大货 | 询价 | 询价 | 询价 |
