AZD2461 is a novel and potent PARP inhibitor with lower affinity to P-glycoprotein. AZD2641 is currently in Phase I clinical study. The study is being conducted to see how it may work to treat solid tumors. The main purpose is to establish a safe dosage of the drug and provide additional information on any potential side effects this drug may cause. The study will also assess the blood levels and action of AZD2461 in the body over a period of time and will indicate whether the drug has a therapeutic effect on solid tumors.
仅供研究使用。 我们不向患者出售。
化学信息
名称 | AZD-2461 |
Iupac 化学名称 | AZD-2461 |
同义词 | AZD2461; AZD-2461; AZD 2461 |
英文同义词 | AZD2461; AZD-2461; AZD 2461 |
分子式 | C22H22FN3O3 |
分子量 | 395.43 |
InChiKey | |
InChi | |
Cas号 | 1174043-16-3 |
相关CAS号 | |
外观性状 | crystalline solid |
纯度 | 98% |
存储 | 3 years -20ºCpowder |
可溶性 | Soluble in DMSO |
处理方式 | |
运输条件 | Shipped under ambient temperature as non-hazardous chemical. |
海关编码 | |
Targets | |
Mechanism | |
Cell study | |
Animal study | |
Clinical study | |