Apoptozole
编号: 161014002
Cas号: 1054543-47-3
纯度: 98% by HPLC
Apoptosis Activator VII, Apoptozole is a cell-permeable imidazole compound that directly binds anti-apoptotic chaperone Hsc70 and its inducible homologue Hsp70 (Kd = 210 and 140 nM, respectively). Apoptozole is shown to effectively inhibit the proliferation of SK-OV-3, HCT-15, and A549 cancer cell lines (IC50 = 220, 250 and 130 nM, respectively) and induce 90% apoptotic cell death in P19 embryonic carcinoma and A549 lung cancer cultures after 12 hours drug treatment (1 M).
仅供研究使用。 我们不向患者出售。
化学信息
| 名称 | Apoptozole |
|---|---|
| 分子式 | C33H24F6N3O3 |
| 分子量 | 625.6 |
| Smile | COc1ccc(cc1)c2c(n(c(n2)c3cc(cc(c3)C(F)(F)F)C(F)(F)F)Cc4ccc(cc4)C(=O)N)c5ccc(cc5)OC |
| InChiKey | ZIMMTPFXOMAJTQ-UHFFFAOYSA-N |
| InChi | InChI=1S/C33H25F6N3O3/c1-44-26-11-7-20(8-12-26)28-29(21-9-13-27(45-2)14-10-21)42(18-19-3-5-22(6-4-19)30(40)43)31(41-28)23-15-24(32(34,35)36)17-25(16-23)33(37,38)39/h3-17H,18H2,1-2H3,(H2,40,43) |
| Cas号 | 1054543-47-3 |
| MDL | MFCD19443178 |
| 相关CAS号 |
订购信息
| 包装 | 价格 | 库存 | 纯度 | 备货期 |
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| 大货 | 询价 | 询价 | 询价 |
