BAY-218, also known as BAY-2335218, is a potent and selective small-molecule AhR inhibitor, as a new modality to counteract tumor immunosuppression.
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名称 | BAY-218 |
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Iupac 化学名称 | (S)-6-(4-chlorophenyl)-2-(3-fluorophenyl)-N-(1-hydroxypropan-2-yl)-3-oxo-2,3-dihydropyridazine-4-carboxamide |
同义词 | BAY-218; BAY 218; BAY218; BAY-2335218; BAY 2335218; BAY2335218; |
英文同义词 | BAY-218; BAY 218; BAY218; BAY-2335218; BAY 2335218; BAY2335218; |
分子式 | C20H17ClFN3O3 |
分子量 | 401.8224 |
InChiKey | RFGRNBWAUZSMBN-LBPRGKRZSA-N |
InChi | InChI=1S/C20H17ClFN3O3/c1-12(11-26)23-19(27)17-10-18(13-5-7-14(21)8-6-13)24-25(20(17)28)16-4-2-3-15(22)9-16/h2-10,12,26H,11H2,1H3,(H,23,27)/t12-/m0/s1 |
Cas号 | 2162982-11-6 |
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