BH3I-1 is an inhibitor of Bcl-xL with IC 50 of 293.95 M. BH3I-1 is a cell permeable BH3 mimetic that binds to Bcl-xL, BH3I-1 can induce cell death. BH3I-1 is a bak activator
BH3I-1 can exerted an antineoplastic effect in thyroid carcinoma cells and sensitized to sublethal concentrations of doxorubicin and bortezomib.
BH3I-1 had a strong sensitizing effect on bortezomib-induced cell death.
仅供研究使用。 我们不向患者出售。
名称 | BH3I-1 |
---|---|
Iupac 化学名称 | BH3I-1 |
同义词 | BHI1; BHI-1; BHI 1; BH 3I1 |
英文同义词 | BHI1; BHI-1; BHI 1; BH 3I1 |
分子式 | C15H14BrNO3S2 |
分子量 | 400.31 |
Smile | CC(C)C(C(=O)O)N1C(=O)/C(=C\c2ccc(cc2)Br)/SC1=S |
InChiKey | COHIEJLWRGREHV-YRNVUSSQSA-N |
InChi | InChI=1S/C15H14BrNO3S2/c1-8(2)12(14(19)20)17-13(18)11(22-15(17)21)7-9-3-5-10(16)6-4-9/h3-8,12H,1-2H3,(H,19,20)/b11-7+ |
Cas号 | 300817-68-9 |
MDL | MFCD03453544 |
相关CAS号 |
包装 | 价格 | 库存 | 纯度 | 备货期 |
---|---|---|---|---|
大货 | 询价 | 询价 | 询价 |