BNC105
编号: 6111023
Cas号: 945771-74-4
纯度: 98%
BNC105 is a tubulin polymerization inhibitor with potent antiproliferative and tumor vascular disrupting properties.
BNC105 exhibited excellent potency against a panel of different cancer cell lines with IC50 <1 nM for DU145, Calu-6, MDA-MB-231 etc. The selectivity observed for BNC105 against activated over quiescent HUVECs was also observed in human aortic arterial endothelial cells (HAAECs). BNC105 also exhibited good potency toward the cisplatin resistant cell line A2780cis.
仅供研究使用。 我们不向患者出售。
化学信息
| 名称 | BNC105 |
|---|---|
| Iupac 化学名称 | BNC105 |
| 同义词 | BNC-105 |
| 英文同义词 | BNC-105 |
| 分子式 | C20H20O7 |
| 分子量 | 372.37 |
| Smile | Cc1c(c2ccc(c(c2o1)O)OC)C(=O)c3cc(c(c(c3)OC)OC)OC |
| InChiKey | RADMJHVVIZTENA-UHFFFAOYSA-N |
| InChi | InChI=1S/C20H20O7/c1-10-16(12-6-7-13(23-2)18(22)19(12)27-10)17(21)11-8-14(24-3)20(26-5)15(9-11)25-4/h6-9,22H,1-5H3 |
| Cas号 | 945771-74-4 |
| MDL | MFCD22628798 |
| 相关CAS号 |
订购信息
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