Benzbromarone is a uricosuric agent and non-competitive inhibitor of xanthine oxidase used in the treatment of gout, especially when allopurinol, a first-line treatment, fails or produces intolerable adverse effects. It is structurally related to the antiarrhythmic amiodarone. Benzbromarone is highly effective and well tolerated, and clinical trials as early as 1981 and as recently as April 2008 have suggested it is superior to both allopurinol, a xanthine oxidase inhibitor but not uricosuric, and probenecid, another uricosuric drug.
仅供研究使用。 我们不向患者出售。
化学信息
名称 | Benzbromarone |
Iupac 化学名称 | Benzbromarone |
同义词 | L2214; L 2214; L-2214; L2214-Labaz; MJ 10061; Narcaricin; Normurat |
英文同义词 | L2214; L 2214; L-2214; L2214-Labaz; MJ 10061; Narcaricin; Normurat |
分子式 | C17H12Br2O3 |
分子量 | 424.088 |
Smile | CCc1c(c2ccccc2o1)C(=O)c3cc(c(c(c3)Br)O)Br |
InChiKey | WHQCHUCQKNIQEC-UHFFFAOYSA-N |
InChi | InChI=1S/C17H12Br2O3/c1-2-13-15(10-5-3-4-6-14(10)22-13)16(20)9-7-11(18)17(21)12(19)8-9/h3-8,21H,2H2,1H3 |
Cas号 | 3562-84-3 |
MDL | MFCD00078962 |
相关CAS号 | |
外观性状 | crystalline solid |
纯度 | 98% |
存储 | 3 years -20ºCpowder |
可溶性 | Soluble in DMSO |
处理方式 | |
运输条件 | Shipped under ambient temperature as non-hazardous chemical. |
海关编码 | |
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Mechanism | |
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