CB1-IN-1 is a peripherally restricted CB1R antagonist, with Ki of 0.3 nM and 21 nM for CB1R (EC50 = 3 nM) and CB2R, respectively.
CB1-IN-1 is a novel peripherally restricted cannabinoid 1 receptor antagonist with significant weight-loss efficacy in diet-induced obese mice. CB1-IN-1 has great potential to ameliorate this related metabolic syndrome.
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名称 | CB1-IN-1 |
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Iupac 化学名称 | CB1-IN-1 |
分子式 | C33H31Cl2F3N6O3S2 |
分子量 | 751.67 |
InChiKey | |
InChi | |
Cas号 | 1429239-98-4 |
相关CAS号 |
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