CF-102
编号: 16053104
Cas号: 163042-96-4
纯度: 98% by HPLC
CF-102, also known as 2-Cl-IB-MECA, is an orally bioavailable, synthetic, highly selective adenosine A3 receptor (A3AR) agonist with potential antineoplastic activity. Adenosine A3 receptor agonist CF102 selectively binds to and activates the cell surface-expressed A3AR, deregulating Wnt and NF-kB signal transduction pathways downstream, which may result in apoptosis of A3AR-expressing tumor cells. A3AR, a G protein-coupled receptor, is highly expressed on the cell surfaces of various solid tumor cell types, including hepatocellular carcinoma (HCC) cells, and plays an important role in cellular proliferation
仅供研究使用。 我们不向患者出售。
化学信息
| 名称 | CF-102 |
|---|---|
| Iupac 化学名称 | (2S,3S,4R,5R)-5-(2-chloro-6-((3-iodobenzyl)amino)-9H-purin-9-yl)-3,4-dihydroxy-N-methyltetrahydrofuran-2-carboxamide |
| 同义词 | CF 102; Cl-IB-MECA; 2-Cl-IB-MECA |
| 英文同义词 | CF 102; Cl-IB-MECA; 2-Cl-IB-MECA |
| 分子式 | C18H18ClIN6O4 |
| 分子量 | 544.73079 |
| Smile | ClC1=NC(=C2N=CN(C2=N1)[C@H]1[C@@H]([C@@H]([C@H](O1)C(=O)NC)O)O)NCC1=CC(=CC=C1)I |
| InChiKey | IPSYPUKKXMNCNQ-PFHKOEEOSA-N |
| InChi | InChI=1S/C18H18ClIN6O4/c1-21-16(29)13-11(27)12(28)17(30-13)26-7-23-10-14(24-18(19)25-15(10)26)22-6-8-3-2-4-9(20)5-8/h2-5,7,11-13,17,27-28H,6H2,1H3,(H,21,29)(H,22,24,25)/t11-,12+,13-,17+/m0/s1 |
| Cas号 | 163042-96-4 |
| 相关CAS号 |
订购信息
| 包装 | 价格 | 库存 | 纯度 | 备货期 |
|---|---|---|---|---|
| 大货 | 询价 | 询价 | 询价 |
