CHIR-99021
编号: 16062904
Cas号: 252917-06-9
纯度: 98% by HPLC
CHIR-99021, also known as CT99021, is a glycogen synthase kinase 3 (GSK3) inhibitor that has antiproliferative activity in vitro and in vivo. CHIR-99021 inhibits GSK-3 with IC50 at 7 nM. In a series of carcinoma cell lines, the IC50 of CHIR99021 for proliferation is about 10M
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化学信息
| 名称 | CHIR-99021 |
|---|---|
| Iupac 化学名称 | 6-((2-((4-(2,4-dichlorophenyl)-5-(4-methyl-1H-imidazol-2-yl)pyrimidin-2-yl)amino)ethyl)amino)nicotinonitrile |
| 同义词 | CHIR99021; CHIR-99021 |
| 英文同义词 | CHIR99021; CHIR-99021 |
| 分子式 | C22H18Cl2N8 |
| 分子量 | 465.34 |
| Smile | ClC1=C(C=CC(=C1)Cl)C1=NC(=NC=C1C=1NC=C(N1)C)NCCNC1=NC=C(C#N)C=C1 |
| InChiKey | AQGNHMOJWBZFQQ-UHFFFAOYSA-N |
| InChi | InChI=1S/C22H18Cl2N8/c1-13-10-29-21(31-13)17-12-30-22(32-20(17)16-4-3-15(23)8-18(16)24)27-7-6-26-19-5-2-14(9-25)11-28-19/h2-5,8,10-12H,6-7H2,1H3,(H,26,28)(H,29,31)(H,27,30,32) |
| Cas号 | 252917-06-9 |
| 相关CAS号 |
订购信息
| 包装 | 价格 | 库存 | 纯度 | 备货期 |
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| 大货 | 询价 | 询价 | 询价 |
