Cerdulatinib (PRT-062070) is an oral active, multi-targeted tyrosine kinase inhibitor with IC50 of 12 nM/6 nM/8 nM/0.5 nM and 32 nM forJAK1/JAK2/JAK3/TYK2 and Syk, respectively. Also inhibits 19 other tested kinases with IC50 less than 200 nM
仅供研究使用。 我们不向患者出售。
化学信息
名称 | Cerdulatinib (PRT062070, PRT2070) |
Iupac 化学名称 | 4-(cyclopropylamino)-2-[[4-[4-(ethylsulfonyl)-1-piperazinyl]phenyl]amino]-5-pyrimidinecarboxamide,hydrochloride (1:1) |
分子式 | C20H28ClN7O3S |
分子量 | 482 |
InChiKey | |
InChi | |
Cas号 | 1369761-01-2 |
相关CAS号 | |
Targets | |
Mechanism | |
Cell study | |
Animal study | |
Clinical study | |