DCVC inhibits pathogen-stimulated TNF- in human extra placental membranes in vitro.
DCVC inhibits pathogen stimulated cytokine release from tissue punch cultures. DCVC (5-50 M) significantly inhibits LTA-, LPS-, and GBS-stimulated cytokine release from tissue cultures as early as 4 h (P 0.05). In contrast, TCA (up to 500 M) does not inhibit LTA-stimulated cytokine release from tissue punches. DCVC effects on LTA-stimulated and LPS-stimulated TNF- release from tissue punch cultures of extraplacental membranes. DCVC effects on GBS-stimulated release of pro-inflammatory cytokines from extraplacental membranes in transwell cultures.
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名称 | DCVC |
---|---|
Iupac 化学名称 | DCVC |
同义词 | S-[(1E)-1,2-dichloroethenyl]--L-cysteine |
英文同义词 | S-[(1E)-1,2-dichloroethenyl]--L-cysteine |
分子式 | C5H7Cl2NO2S |
分子量 | 216.09 |
Smile | C([C@@H](C(=O)O)N)S/C(=C\Cl)/Cl |
InChiKey | PJIHCWJOTSJIPQ-PEQLYWQKSA-N |
InChi | InChI=1S/C5H7Cl2NO2S/c6-1-4(7)11-2-3(8)5(9)10/h1,3H,2,8H2,(H,9,10)/b4-1-/t3-/m0/s1 |
Cas号 | 13419-46-0 |
MDL | MFCD00870277 |
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