DSR-6434
编号: 20497
Cas号: 1059070-10-8
纯度: 98% Min.
DSR-6434 is a potent TLR7 agonist (EC50 = 7.2 nM). DSR-6434 activates several immune effector cells in vitro. DSR-6434 indicated an optimal balance between the agonistic potency and high water solubility. It also demonstrated a strong antitumor effect in vivo by intravenous administration in a tumor bearing mice model.
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化学信息
| 名称 | DSR-6434 |
|---|---|
| Iupac 化学名称 | 6-Amino-2-(butylamino)-9-[[6-[2-(dimethylamino)ethoxy]-3-pyridinyl]methyl]-7,9-dihydro-8H-purin-8-one |
| 同义词 | DSR-6434; DSR 6434; DSR6434; |
| 英文同义词 | DSR-6434; DSR 6434; DSR6434; |
| 分子式 | C19H28N8O2 |
| 分子量 | 400.48 |
| Smile | O=C1NC2=C(N)N=C(NCCCC)N=C2N1CC3=CC=C(OCCN(C)C)N=C3 |
| InChiKey | SSZHESNDOMBSRV-UHFFFAOYSA-N |
| InChi | InChI=1S/C19H28N8O2/c1-4-5-8-21-18-24-16(20)15-17(25-18)27(19(28)23-15)12-13-6-7-14(22-11-13)29-10-9-26(2)3/h6-7,11H,4-5,8-10,12H2,1-3H3,(H,23,28)(H3,20,21,24,25) |
| Cas号 | 1059070-10-8 |
| 相关CAS号 |
订购信息
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