Debio-1347
编号: 16122928
Cas号: 1265229-25-1
纯度: 98%
Debio-1347, also known as FF284 and CH5183284, is an orally bioavailable inhibitor of the fibroblast growth factor receptor subtypes 1 (FGFR-1), 2 (FGFR-2) and 3 (FGFR-3), with potential antineoplastic activity. FGFR inhibitor debio 1347 binds to and inhibits FGFR-1, -2, and -3, which result in the inhibition of FGFR-mediated signal transduction pathways. This leads to the inhibition of both tumor cell proliferation and angiogenesis, and causes cell death in FGFR-overexpressing tumor cells.
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化学信息
| 名称 | Debio-1347 |
|---|---|
| Iupac 化学名称 | Debio-1347 |
| 同义词 | Debio 1347; Debio1347; CH5183284; CH 5183284; CH-5183284; FF284; FF-284; FF 284 |
| 英文同义词 | Debio 1347; Debio1347; CH5183284; CH 5183284; CH-5183284; FF284; FF-284; FF 284 |
| 分子式 | C20H16N6O |
| 分子量 | 356.38 |
| Smile | NC1=C(C=NN1C1=CC2=C(N=C(N2)C)C=C1)C(=O)C=1NC2=CC=CC=C2C1 |
| InChiKey | BEMNJULZEQTDJY-UHFFFAOYSA-N |
| InChi | InChI=1S/C20H16N6O/c1-11-23-16-7-6-13(9-17(16)24-11)26-20(21)14(10-22-26)19(27)18-8-12-4-2-3-5-15(12)25-18/h2-10,25H,21H2,1H3,(H,23,24) |
| Cas号 | 1265229-25-1 |
| 相关CAS号 |
订购信息
| 包装 | 价格 | 库存 | 纯度 | 备货期 |
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| 大货 | 询价 | 询价 | 询价 |
