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Defactinib

编号: 16122929
Cas号: 1073160-26-5
纯度: 98% 

Defactinib, also known as VS-6063 and PF04554878, is an orally bioavailable, small-molecule focal adhesion kinase (FAK) inhibitor with potential antiangiogenic and antineoplastic activities. Defactinib inhibits FAK, which may prevent the integrin-mediated activation of several downstream signal transduction pathways, including those involving RAS/MEK/ERK and PI3K/Akt, thus inhibiting tumor cell migration, proliferation, survival, and tumor angiogenesis. 

仅供研究使用。 我们不向患者出售。

化学信息

名称Defactinib
Iupac 化学名称1073160-26-5 
同义词Defactinib hydrochloride; Defactinib HCl; VS6063; VS 6063; VS-6063; PF04554878; PF-04554878; PF 04554878; PF4554878; PF-4554878; PF4554878 
英文同义词Defactinib hydrochloride; Defactinib HCl; VS6063; VS 6063; VS-6063; PF04554878; PF-04554878; PF 04554878; PF4554878; PF-4554878; PF4554878 
分子式C20H22ClF3N8O3S 
分子量546.9542 
InChiKey
InChi
Cas号1073160-26-5
相关CAS号

订购信息

包装价格库存纯度备货期
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外观性状crystalline solid 
纯度98% 
存储3 years -20ºCpowder 
可溶性Soluble in DMSO 
处理方式
运输条件Shipped under ambient temperature as non-hazardous chemical. 
海关编码
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

化学结构

16122929 - Defactinib | CAS 1073160-26-5

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