Dorsomorphin(Compound C; BML-275) has been shown to act as a potent and selective inhibitor of AMPK (AMP-activated protein kinase; Ki = 109 nM), induced by AICAR and metformin; also inhibits the bone morphogenetic protein type 1 receptors ACTR-I (ALK2), B
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化学信息
名称 | Dorsomorphin |
分子式 | C24H25N5O |
分子量 | 399.49 |
Smile | c1cc(ccc1c2cnc3c(cnn3c2)c4ccncc4)OCCN5CCCCC5.Cl.Cl |
InChiKey | RJDVIJJQKMGPMV-UHFFFAOYSA-N |
InChi | InChI=1S/C24H25N5O.2ClH/c1-2-12-28(13-3-1)14-15-30-22-6-4-19(5-7-22)21-16-26-24-23(17-27-29(24)18-21)20-8-10-25-11-9-20;;/h4-11,16-18H,1-3,12-15H2;2*1H |
Cas号 | 866405-64-3 |
MDL | MFCD11112197 |
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