ETC-1002,also known as Bempedoic acid, is an orally available, once-daily LDL-C lowering small molecule designed to lower elevated levels of LDL-C and to avoid side effects associated with existing LDL-C lowering therapies.ETC-1002 is an activator of hepatic AMP-activated protein kinase (AMPK). It has potent inhibitory activity against hepatic ATP-citrate lyase(IC50=29 uM).
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名称 | ETC-1002 |
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Iupac 化学名称 | ETC-1002 |
同义词 | Bempedoic acid, ESP-55016 |
英文同义词 | Bempedoic acid, ESP-55016 |
分子式 | C19H36O5 |
分子量 | 344.49 |
Smile | CC(C)(CCCCCC(CCCCCC(C)(C)C(=O)O)O)C(=O)O |
InChiKey | HYHMLYSLQUKXKP-UHFFFAOYSA-N |
InChi | InChI=1S/C19H36O5/c1-18(2,16(21)22)13-9-5-7-11-15(20)12-8-6-10-14-19(3,4)17(23)24/h15,20H,5-14H2,1-4H3,(H,21,22)(H,23,24) |
Cas号 | 738606-46-7 |
MDL | MFCD18800820 |
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