Etelcalcetide
编号: 16071011
Cas号: 1334237-71-6
纯度: 98% by HPLC
Etelcalcetide, also known as AMG 416 and KAI-4169, is a D-amino peptide calcimimetic undergoing clinical evaluation for the treatment of secondary hyperparathyroidism for patients with chronic kidney disease (CKD) on hemodialysis. Etelcalcetide is administered intravenously at the end of each dialysis session. It functions by binding to and activating the calcium-sensing receptor (CaSR) in the parathyroid gland as an allosteric activator, resulting in PTH reduction and suppression. Elevated PTH is often observe in patients with CKD. On August 25, 2015 Amgen Inc. announced its submission of a New Drug Application to the Food and Drug Administration for etelcalcetide.
仅供研究使用。 我们不向患者出售。
化学信息
| 名称 | Etelcalcetide |
|---|---|
| Iupac 化学名称 | N-Acetyl-D-cysteinyl-D-alanyl-D-arginyl-D-arginyl-D-arginyl-D-alanyl-D-argininamide disulfide with L-cysteine hydrochloride |
| 同义词 | AMG 416; AMG-416 |
| 英文同义词 | AMG 416; AMG-416 |
| 分子式 | C38H74ClN21O10S2 |
| 分子量 | 1084.717 |
| InChiKey | |
| InChi | |
| Cas号 | 1334237-71-6 |
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订购信息
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