GDC-0853
编号: 16123004
Cas号: 1434048-34-6
纯度: 98%
GDC-0853 is orally available inhibitor of Bruton's tyrosine kinase (BTK) with potential antineoplastic activity. Upon administration, GDC-0853 inhibits the activity of BTK and prevents the activation of the B-cell antigen receptor (BCR) signaling pathway. This prevents both B-cell activation and BTK-mediated activation of downstream survival pathways, which leads to the inhibition of the growth of malignant B-cells that overexpress BTK. BTK, a member of the Src-related BTK/Tec family of cytoplasmic tyrosine kinases, is overexpressed in B-cell malignancies; it plays an important role in B-lymphocyte development, activation, signaling, proliferation and survival.
仅供研究使用。 我们不向患者出售。
化学信息
| 名称 | GDC-0853 |
|---|---|
| Iupac 化学名称 | GDC-0853 |
| 同义词 | GDC 0853; GDC0853; RG-7845; RG7845; RG 7845 |
| 英文同义词 | GDC 0853; GDC0853; RG-7845; RG7845; RG 7845 |
| 分子式 | C37H44N8O4 |
| 分子量 | 664.811 |
| InChiKey | |
| InChi | |
| Cas号 | 1434048-34-6 |
| 相关CAS号 |
订购信息
| 包装 | 价格 | 库存 | 纯度 | 备货期 |
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| 大货 | 询价 | 询价 | 询价 |
