Inauhzin(INZ) is a novel small molecule that effectively reactivates p53 by inhibiting SIRT1 activity, promotes p53-dependent apoptosis of human cancer cells without causing apparently genotoxic stress(IC50=3 uM, in A549 cell).
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化学信息
名称 | Inauhzin |
分子式 | C25H19N5OS2 |
分子量 | 469.58 |
InChiKey | |
InChi | |
Cas号 | 309271-94-1 |
相关CAS号 | |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study | |