Iniparib
编号: 16071103
Cas号: 160003-66-7
纯度: 98% by HPLC
Iniparib, also known as BSI-201, is a small-molecule prodrug inhibitor of the nuclear enzyme poly(ADP-ribose) polymerase-1 (PARP-1) with potential chemosensitizing, radiosensitizing and antineoplastic activities. In vivo, PARP-1 inhibitor BSI-201 is converted to the active drug, which selectively binds to PARP-1 and inhibits PARP-1- mediated DNA repair. Consequently, this agent may enhance the cytotoxicity of DNA-damaging agents and reverse tumor cell resistance to chemotherapy and radiation therapy. In addition, PARP-1 inhibitor BSI-201 may exhibit direct antineoplastic activity against cancers defective in DNA repair.
仅供研究使用。 我们不向患者出售。
化学信息
| 名称 | Iniparib |
|---|---|
| Iupac 化学名称 | 4-iodo-3-nitrobenzamide |
| 同义词 | BSI-201; BSI201 |
| 英文同义词 | BSI-201; BSI201 |
| 分子式 | C7H5IN2O3 |
| 分子量 | 292.03067 |
| Smile | IC1=C(C=C(C(=O)N)C=C1)[N+](=O)[O-] |
| InChiKey | MDOJTZQKHMAPBK-UHFFFAOYSA-N |
| InChi | InChI=1S/C7H5IN2O3/c8-5-2-1-4(7(9)11)3-6(5)10(12)13/h1-3H,(H2,9,11) |
| Cas号 | 160003-66-7 |
| 相关CAS号 |
订购信息
| 包装 | 价格 | 库存 | 纯度 | 备货期 |
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