Itacitinib
编号: 6111505
Cas号: 1334298-90-6
纯度: 98%
Itacitinib (INCB039110) is an oral selective JAK1 inhibitor.
Itacitinib is an inhibitor of the Janus kinases (JAKs) with selectivity for JAK1. Itacitinib potently inhibits OCT2-mediated uptake of creatinine as well as MATE1-/MATE2-K-mediated efflux of creatinine. Itacitinib causes a dose-dependent decrease in transcellular transport of creatinine with weaker net inhibition compared with the effects on individual transporters.
仅供研究使用。 我们不向患者出售。
化学信息
| 名称 | Itacitinib |
|---|---|
| Iupac 化学名称 | Itacitinib |
| 同义词 | INCB039110; INCB-039110; INCB 039110 |
| 英文同义词 | INCB039110; INCB-039110; INCB 039110 |
| 分子式 | C26H23F4N9O |
| 分子量 | 553.51 |
| InChiKey | |
| InChi | |
| Cas号 | 1334298-90-6 |
| 相关CAS号 |
订购信息
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