Kenpaullone
编号: 16122711
Cas号: 142273-20-9
纯度: 98%
Kenpaullone is an ATP-competitive inhibitor of cyclin-dependent kinases (CDKs). It also inhibit glycogen synthase kinase 3 (GSK3) with IC50 of 0.23 M. Kenpaullone also induces the dephosphorylation of both GSK3 isoforms in SH-SY5Y cells and PC12 cells. Kenpaullone (20M) strongly suppresses the autophosphorylation of GSK3 at Tyr216 in vitro whether GSK3 is expressed in Sf21 cells or in E. coli
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化学信息
| 名称 | Kenpaullone |
|---|---|
| Iupac 化学名称 | Kenpaullone |
| 同义词 | N/A |
| 英文同义词 | N/A |
| 分子式 | C16H11BrN2O |
| 分子量 | 327.18 |
| Smile | c1ccc2c(c1)-c3c(c4cc(ccc4[nH]3)Br)CC(=O)N2 |
| InChiKey | QQUXFYAWXPMDOE-UHFFFAOYSA-N |
| InChi | InChI=1S/C16H11BrN2O/c17-9-5-6-14-11(7-9)12-8-15(20)18-13-4-2-1-3-10(13)16(12)19-14/h1-7,19H,8H2,(H,18,20) |
| Cas号 | 142273-20-9 |
| MDL | MFCD02683595 |
| 相关CAS号 |
订购信息
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