L67 is a DNA Ligase Inhibitor. L67 inhibited DNA ligases I and III. L67 is a simple competitive inhibitor with respect to nicked DNA. L67 inhibits DNA ligases I and III with IC₅₀ values of 10 M and 10 M.). L67 significantly increased the cytotoxicity of DNA-damaging.
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化学信息
名称 | L67 |
Iupac 化学名称 | L67 |
同义词 | L-67; L 67 |
英文同义词 | L-67; L 67 |
分子式 | C16H14Br2N4O4 |
分子量 | 486.12 |
InChiKey | |
InChi | |
Cas号 | 325970-71-6 |
相关CAS号 | |
外观性状 | crystalline solid |
纯度 | 98% |
存储 | 3 years -20ºCpowder |
可溶性 | Soluble in DMSO |
处理方式 | |
运输条件 | Shipped under ambient temperature as non-hazardous chemical. |
海关编码 | |
Targets | |
Mechanism | |
Cell study | |
Animal study | |
Clinical study | |