LDK378(Ceritinib) is potent inhibitor against ALK with IC50 of 0.2 nM, shows 40- and 35-fold selectivity against IGF-1R and InsR, respectively.
仅供研究使用。 我们不向患者出售。
化学信息
名称 | LDK378 |
分子式 | C28H36ClN5O3S |
分子量 | 558.14 |
InChiKey | |
InChi | |
Cas号 | 1032900-25-6 |
相关CAS号 | |
纯度 | 98% |
可溶性 | 10 mM in DMSO |
处理方式 | |
海关编码 | |
Targets | |
Mechanism | |
Cell study | |
Animal study | |
Clinical study | |