Lirafugratinib HCl
编号: 24113
Cas号: 2688040-45-9
纯度: 98% Min.
Lirafugratinib, also known as RLY-4008, is a tyrosine kinase inhibitor with potential antineoplastic activity. Lirafugratinib binds to and inhibits FGFR2, which results in the inhibition of FGFR2-mediated signal transduction pathways. This inhibits the proliferation of FGFR2-overexpressing tumor cells. FGFR2, a receptor tyrosine kinase upregulated in many tumor cell types, plays a key role in cellular proliferation, migration and survival.
仅供研究使用。 我们不向患者出售。
化学信息
| 名称 | Lirafugratinib HCl |
|---|---|
| Iupac 化学名称 | N-[4-[4-amino-5-[3-fluoro-4-(4-methylpyrimidin-2-yl)oxyphenyl]-7-methylpyrrolo[2,3-d]pyrimidin-6-yl]phenyl]-2-methylprop-2-enamide;hydrochloride |
| 同义词 | Lirafugratinib Hydrochloride; Lirafugratinib HCl, RLY-4008; RLY 4008; RLY4008; |
| 英文同义词 | Lirafugratinib Hydrochloride; Lirafugratinib HCl, RLY-4008; RLY 4008; RLY4008; |
| 分子式 | C28H25ClFN7O2 |
| 分子量 | 546.00 |
| Smile | C=C(C)C(NC1=CC=C(C2=C(C3=CC=C(OC4=NC=CC(C)=N4)C(F)=C3)C5=C(N)N=CN=C5N2C)C=C1)=O.[H]Cl |
| InChiKey | HLGJPRBWELSHLI-UHFFFAOYSA-N |
| InChi | InChI=1S/C28H24FN7O2.ClH/c1-15(2)27(37)35-19-8-5-17(6-9-19)24-22(23-25(30)32-14-33-26(23)36(24)4)18-7-10-21(20(29)13-18)38-28-31-12-11-16(3)34-28;/h5-14H,1H2,2-4H3,(H,35,37)(H2,30,32,33);1H |
| Cas号 | 2688040-45-9 |
| 相关CAS号 |
订购信息
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